Course Name

Vaccine & immunotherapy

Summary

Lecture Objectives

• This course is designed for graduate students to learn essential concepts, advanced knowledge, and recent R&D trends for vaccines and immunotherapies. Basic immunological concepts will be explained for solid understanding, and crucial principles and recent advances in prophylactic vaccines for infectious disease, therapeutic vaccines, anti-tumor immunotherapies will be covered using a textbook and seminal scientific papers.

Course Name

Molecular Virology

Summary

Lecture Objectives

• This class will cover a diverse families of animal viruses with emphasis on molecular aspects of viral life cycle. Features such as virus structure, viral genome organization, genome replication as well as host immune response will be discussed.

Course Name

Bacterial infection and antibiotic resistance

Summary

Lecture Objectives

• Infections caused by antibiotic resistant bacteria is a global public health threat, accounting for more than 40% of hospital acquired infections causing over 23,000 and 24,000 deaths in the United States and EU countries, respectively. Antibiotic resistance is also threatening public health in Korea, one of the countries with the high prescription rate of antibiotics among OECD countries. In 2014, superbacteria that are resistant to all existing antibiotics were found in Korea and a recent report confirmed that antibiotic resistance rates of major pathogenic bacteria are already seriously high in Korea showing 85.7% of methicillin resistance in clinically isolated Staphylococcus aureus. This lecture is designed for graduate students in the field of biomedical science to provides basic knowledge of antibiotics along with mechanisms and development of antibiotics resistance.

Course Name

Principles of drug discovery

Summary

Lecture Objectives

• This lecture helps students to understand the basics of new drug development methodology for small molecule compounds, and covers the latest technologies and trends to understand novel drug development. The lecture will cover drug development technologies such as pharmaceutical chemistry, analytical chemistry. Hands-on experiment of synthesizing small molecules as drug candidates will help in learning the drug discovery process. Also, AI based drug development technologies such as molecular modeling, chembioinformatics (machine learning) will be covered as enhanced applications. It aims to acquire knowledge about the development of therapeutic agents such as antibiotics, antivirals, and anticancer drugs using these technologies.

Course Name

Applied Biochemistry in Drug Discovery

Summary

Lecture Objectives

• Drug discovery process is at the interface between chemistry and biology. We will review fundamentals of biochemistry, focusing particularly on protein components that constitute a cell or a pathogen and their interaction with metabolites as well as other cellular polymers, and drugs. Standard techniques as well as new approaches will be presented and analyzed all along, in order to have a better understanding of the research landscape in drug discovery.

Course Name

Advanced technologies in drug discovery

Summary

Lecture Objectives

• How technology could transform drug research? In recent years, beyond recognition technological advances have changed the drug discovery process. This course will address today key technologies as well as emerging technologies in drug discovery which are key to prepare the future generation of scientists. Image based analysis and methodologies as the core technology for advancement in drug discovery will be covered in the course. They will learn to adapt the way drug discovery and drug development work together to succeed in an increasingly uncertain environment.

Course Name

Applied Parasitology

Summary

Lecture Objectives

• This lecture offers basic knowledge on pathogenic parasites that is widely distributed globally. The basics of infection biology on malaria, toxoplasmosis, leishmaniasis and etc will be covered, and application of molecular biology, biochemistry, biophysics, molecular modelling technique to discover novel drug will be introduced.

Course Name

Preclinical Laboratory Animal Medicine

Summary

Lecture Objectives

• This curriculum is designed to learn knowledge about animal experiments conducted for basic medicine, new drug development, and investigation of life phenomena. In particular, for the implementation of animal experiments conducted for infectious disease research, this course provide specific information about pre-experiment procedures such as animal ethics and handling of pathogens and actual experiments such as administration methods, blood sampling methods, and autopsy methods. This course also provide the information about the use of animal biosatety facilities, which are indispensable for research and development of new drugs for infectious diseases, and consider various incidents that may occur during animal experiments. This curriculum aims too improve understanding of preclinical research by acquiring general knowledge of the animal experiment stage for new drug development.

Course Name

Advanced technology & application of anticancer drug discovery

Summary

Lecture Objectives

• This curriculum aims to enable students to learn the latest advanced drug discovery techniques which have physiological relevance and analysis method for anticancer drug development through papers and trend reports, and to deal with various application methods. At the same time, it aims to achieve the design of a customized drug discovery strategy that reflects the tissue specificity of various cancers by acquiring extensive knowledge of the latest cancer biology.